Audio / Video

Physics/SQB Presents

  • 00:49:20

Description

Embryology at the beginning of the 21st century finds itself in a situation similar to neurobiology; the behavior of the component pieces is understood in some detail, but how they self-assemble to become life is still very hazy. There are 100’s of molecules that enable cell communication and genetics defines their function by classifying aberrant embryos at a suitable intermediate stage of development, which is difficult for mammals and impossible for humans. Embryonic stem cells can be expanded indefinitely and in the context of the embryo give rise to all cells in the body. The colloquium will describe synthetic systems that coax these stem cells to recapitulate aspects of gastrulation, which is the process by which the embryo transforms from a sphere to a cylinder, builds its anterior-posterior and dorsal-ventral axes, and segregates cells into ectoderm (skin and neurons), mesoderm (muscle bones and blood), and endoderm (gut lungs pancreas etc) lineages.

Details

Title

Physics/SQB Presents

Creator

University of California, Berkeley. Dept. of Physics

Published

Berkeley, CA, University of California, Berkeley, Dept. of Physics, March 4, 2019

Full Collection Name

Physics Colloquia

Type

Video

Format

Lecture.

Extent

1 streaming video file

Other Physical Details

digital, sd., col.

Archive

Physics Library

Note

Recorded at a colloquium held on March 4, 2019, sponsored by the Dept. of Physics, University of California, Berkeley.

originally produced as an .mts file in 2019

Speakers: Eric D Siggia.

Collection

Physics Colloquia

Tracks

colloquia/3-4-19Siggia.mp4 00:49:20

Linked Resources

View record in Digital Collections.